Lantern Pharma (NASDAQ: LTRN), a clinical-stage biopharmaceutical company using its RADR(R) AI platform to transform oncology drug discovery and development, presented clinical data from its ongoing Phase 1 trial of LP-284 at the 25th Annual Lymphoma, Leukemia & Myeloma Congress in New York City, showing a confirmed complete metabolic response in a 41-year-old patient with aggressive Grade 3 non-germinal center B-cell diffuse large B-cell lymphoma after failure of four prior regimens, including CAR-T and bispecific antibody therapies. The response, achieved after two 28-day cycles of LP-284, supports the drug’s synthetic lethal mechanism and potential to fill a critical post-immunotherapy treatment gap. Lantern CEO Panna Sharma said the results validate the company’s AI-driven approach and highlight LP-284’s dual potential as a monotherapy and in combination with FDA-approved agents such as rituximab. Lantern noted LP-284’s favorable early safety profile, multiple FDA Orphan Drug Designations, strong IP protection through 2039, and partnership opportunities for expanding hematology portfolios.
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About Lantern Pharma
Lantern Pharma (NASDAQ: LTRN) is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR(R), leverages over 200 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies that span multiple cancer indications, including both solid tumors and blood cancers and an antibody-drug conjugate (ADC) program. Our lead development programs include a Phase 2 clinical program and multiple Phase 1 clinical trials. Our AI-driven pipeline of innovative product candidates is estimated to have a combined annual market potential of over $15 billion USD and have the potential to provide life-changing therapies to hundreds of thousands of cancer patients across the world.
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