Genes That Saved People from Bubonic Plague Linked to Autoimmune Conditions Today
More than 700 years ago, a pandemic called the Black Death tore across Europe, taking an estimated 75 million to 200 million lives and reducing the continent’s population by around 30% to 60%. The Black Death was the first wave of a pandemic that lasted almost 500 years and is said to be the largest-ever catastrophe involving infectious diseases. Centuries later, the genetic traits that enabled people to fight off the bubonic plague are associated with an increased risk of certain autoimmune disorders. Researchers studying DNA from survivors and victims of the bubonic plague found that people who had a…