Brain Organoids Uncover Autism Biology, Possible Treatments
Researchers at the Scripps Research Institute have uncovered new information about autism spectrum disorder (ASD). ASD is a developmental and neurological disorder that affects how an individual interacts with others, behaves, learns and communicates. The disorder’s causes are only partly known, with scientists linking a number of genetic variants to it. For their study, the researchers used stem cells generated from patients with a severe and rare form of the developmental disorder. They focused on MEF2C haploinsufficiency syndrome (MHS), which develops following a genetic variation in the MEF2 gene. They grew the stem cells into mini-brain organoids, which allowed the…