UCLA Researchers Develop Method to Fix Fuel Shortages in Cancer Immunotherapy
Many immunotherapies developed to combat cancer fail because the CAR-T cells become exhausted after being starved of oxygen in the tumor environment. A new preclinical study conducted by a team at UCLA has uncovered a method to deliver needed glucose to immune cells in a way that tumor cells cannot hijack. This offers hope of keeping anti-cancer fighter cells active and deadly to both solid and non-solid tumors. The study, whose findings appeared in Cell journal, documents how the researchers found a way to keep the oxygen supply of CAR-T cells intact in a way that cancer cells cannot steal and starve the immune cells. They…











