Major Discovery Could Reshape Cancer Immunotherapy
Researchers seeking new ways of fighting cancer using immunotherapy have discovered a “hidden brake” that had previously been unknown to scientists. This brake exists on immune cells and scales back their ability to combat cancer, and it acts without any influence from tumor cells. This molecule, dubbed SLAMF6, occurs naturally on fighter immune cells called T-cells. It is an inbuilt weakness on those cells and it shuts off T-cells’ capacity to kill tumor cells. In preclinical trials, the researchers turned off this switch and were able to revive the immune cells’ ability to combat cancer. The study, whose findings were…
