Immunotherapy Could Be Boosted by Blocking the Removal of Cancer RNA
The immune system is capable of identifying and attacking cancer cells in the body. This process depends on the tumor producing damaged RNA, which then sticks to cell surfaces and provides the antigens that the body identifies as foreign and therefore targets. However, a natural mechanism within the body that removes faulty RNA ironically aids many cancers to avoid detection and therefore limit immune system responses to the disease. Now, a new preclinical study has found that targeting and blocking this clean-up mechanism can allow cancer antigens to express on tumor cells and allow the immune system to quickly identify and attack them. The study was conducted by a University…
