Study Explores Starving Malignant Cells to Boost Immunotherapy, Improve DNA Damage
Prostate cancer is challenging to treat, especially when the disease progresses to a castrate-resistant metastatic state. Conventional treatments, such as hormonal treatments, radiotherapy and chemotherapy, fail most times because of acquired resistance, off-target effects and toxicities. It is well-known that amino acids perform important metabolic functions. While normal cells have lower demand for amino acids, cancer cells exhibit high demand for amino acids because of increased demand for cellular building blocks and energy. Now a new study has determined that starving cancer cells may help improve immunotherapy response and increase damage to DNA, which in turn helps speed up death…
