NewsRoom Articles - Page 62 of 222

TuesdayNov 21, 2023 2:16 pm

Study Finds DNA Loops in Brain Tumors in Kids Amplify Relapse Risk

Medulloblastoma is a rare type of brain tumor that is primarily found in children. It is estimated that about 350 cases of this illness are diagnosed annually. This cancer often resists treatment, which involves a combination of radiation, surgery and chemotherapy. This, combined with the disease’s various subtypes, has made it harder for scientists to develop new therapies. Now, new research has discovered that medulloblastoma patients with tumors that contain circular extrachromosomal DNA have a heightened risk of relapse and mortality. For their research, the scientists compiled a database of patients with medulloblastoma using data from patients diagnosed at Rady’s…

TuesdayNov 21, 2023 9:45 am

Longeveron Inc. (NASDAQ: LGVN) Encouraged by Positive Results from Phase 2a Trial in Patients with Mild AD; Explores Paths Forward for the Development of Lomecel-B(TM)

Longeveron recently released topline results from its Phase 2a trial evaluating Lomecel-B(TM) as a potential treatment for mild AD The study met its primary safety endpoint across all four study groups and showed positive and statistically significant results in secondary endpoint involving the Composite Alzheimer’s Disease Score (“CADS”) for Lomecel-B(TM) and components of the CADS The positive results are expected to form the basis for further development of Lomecel-B(TM) as a potential treatment for mild AD Longeveron (NASDAQ: LGVN), a clinical-stage biotechnology company developing cellular therapies for aging-related and life-threatening conditions for which there is an unmet medical need, announced…

MondayNov 20, 2023 3:24 pm

Study Shows Patients Afflicted by Inflammatory Arthritis Face Numerous Mental Challenges at Work

A new study has found that individuals with inflammatory arthritis are plagued with psychological challenges that make it hard for them to maintain employment. The study, conducted by the Hospital for Special Surgery, was recently presented at the American College of Rheumatology Convergence 2023. One of the researchers involved in the study, Joan Westreich, stated that research had indicated that individuals suffering from inflammatory arthritis had a heightened risk for work disability, which could greatly impact their lives. Westreich also that within a decade of diagnosis, about 40% of those living with this condition wouldn’t be able to work. While…

FridayNov 17, 2023 11:25 am

Study Examines Role of African Sleeping Sickness in Body Wasting

African trypanosomiasis is a progressive illness that affects both humans and animals. The illness is caused by a parasite known as Trypanosoma brucei (T. brucei). In the course of infection, T. brucei colonizes adipose tissue and rapidly grows in the host. This, researchers theorize, may cause weight loss because it primarily affects the biggest visceral adipose tissue depot, the gonadal AT. The infection works by offsetting the balance between anabolism and catabolism, which takes place in the adipocytes’ lipid droplets. An increase in lipid catabolism then causes degradation of triacylglycerol, which is hydrolyzed by lipase, monoacylglycerol lipase and adipose triglyceride…

ThursdayNov 16, 2023 2:10 pm

Study Links Cat Parasite to Accelerated Frailty in Aging People

Toxoplasma gondii (T. gondii) is a single-cell parasite that can cause severe physical and mental conditions. This parasite is known to trigger risky behavior in hosts. The most common way for an individual to be exposed to this parasite is when disposing of cat litter. This is because while the parasite does affect rodents and birds, it thrives in cats. In felines, it can multiply in the cat’s intestines, with its eggs being excreted for easier and faster transmission. While the parasite can stay alive in the host for a long time, most healthy individuals rarely present with symptoms because…

ThursdayNov 16, 2023 9:45 am

Clene Inc. (NASDAQ: CLNN) Reports Q3 2023 Financial Results, Recent Operating Highlights for Its ALS Clinical Program

Clene recently released its financial results for the third quarter ended September 30, 2023, and provided recent operating highlights for its ALS clinical program The ALS clinical program includes two independent studies evaluating the safety and efficacy of the company’s lead investigational product CNM-Au8(R) The 24-month long-term data cut from the open-label extension of the RESCUE-ALS study showed a significant median survival benefit of 19.3 months, a significant 52% decreased risk of ALS clinical worsening events, and a 75% decreased risk of long-term all-cause mortality Clene also summarized long-term follow-up data from the HEALEY ALS platform trial, which demonstrated significantly…

WednesdayNov 15, 2023 1:48 pm

Blood Test Could Detect Worsening MS Symptoms in Patients

Multiple sclerosis is a chronic illness that affects an individual’s brain and spinal cord, resulting in problems moving one’s arms or legs, issues with vision, and problems with balance or sensation. While the cause of this disease is still not known, researchers theorize that it may be caused by the immune system of an individual attacking its own tissues. Estimates show that roughly 2.8 million individuals around the globe live with this illness. The disease’s symptoms often get worse as time goes by, which lowers the quality of life of some patients. Dr. Ari J. Green, cosenior author of a…

TuesdayNov 14, 2023 3:17 pm

New, Deadly Infectious Diseases Could Emerge as Climate Change Worsens

Researchers believe worsening climate change could lead to the emergence of new and deadly infectious diseases. Climate change has the potential to significantly alter weather patterns globally and is already contributing to extreme weather events in several regions. A recent study from the Barcelona Supercomputing Center-Centro Nacional de Supercomputación (BSC-CNS) and the Institute for Research in Biomedicine (IRB Barcelona) has revealed that climate change could also contribute to the proliferation of more deadly infectious diseases. Infectious diseases are the bane of a connected world. As with COVID-19, these diseases have the potential to quickly spill across borders, infect million, and…

TuesdayNov 14, 2023 9:30 am

PaxMedica Inc. (NASDAQ: PXMD) Is Hoping to Boost Patient Independence with Potential ASD Treatment Amid Growing Prevalence Rates

PaxMedica is developing PAX-101, which utilizes the company’s proprietary source of suramin sodium, for the treatment of ASD (Autism Spectrum Disorder) There is no FDA-approved treatment for the core symptoms of autism, even though the rates of autism spectrum disorder have jumped significantly from 2000 to 2020 ASD is characterized by deficits in social communication, restricted and repetitive patterns of behavior, and significant impairment in functioning, three core aspects of the disease that PaxMedica aims to address The company announced positive topline results from a Phase 2 study evaluating PAX-101 as a potential treatment for ASD and hopes to replicate…

MondayNov 13, 2023 12:55 pm

How Immunotherapy Is Cementing a Role in Cancer Treatment

After decades of dominating cancer treatment protocols across the globe, surgery, radiation and chemotherapy are facing increased competition from a fourth treatment option: immunotherapy. Miami Cancer Institute’s CEO and executive medical director Dr. Micahel Zinner notes that cancer treatments traditionally involve using surgery to remove as much of the cancerous tumor as possible followed by chemotherapy or radiation to kill off the remaining cancer cells. While these treatments aren’t fully effective and often have many negative side effects, they have saved millions of lives worldwide over the decades. However, some pundits are now referring to immunotherapy, a relatively new cancer…