Novel Type of Immunotherapy Exhibits Efficacy Against Brain Tumors in Mouse Models
A multi-institutional team of researchers has developed a novel type of cellular immunotherapy that has proven its therapeutic effectiveness in mouse models. Comprised of a researcher from the German Cancer Research Center and a University Medical Center Mannheim physician, the team used NLGN4X-specific T cells to successfully kill brain tumor cells from mice. NLGN4X (Neuroligin4X) is a protein that is involved in protein formation, and it occurs in large amounts in glioblastoma tumor cells even though they are barely present in healthy brain tissue. Glioblastoma is a type of brain cancer that originates in the nerve cell astrocytes within the…











