NewsRoom Articles - Page 9 of 229

TuesdayDec 16, 2025 10:00 am

Researchers Use Supplements to Produce Remarkable Outcomes in Brain Cancer Treatment

A new study done in India has produced results that bring into question the longstanding assumption that treating cancer requires tumors to be destroyed. The researchers attained remarkable results by using another approach, treating the tumor rather than attacking it, and their approach was effective in taming the aggressiveness of glioblastoma while also toning down many biomarkers that indicate the severity of the cancer. For a while, many researchers have been growing in conviction that the way cancer is treated needs to change from efforts geared at destroying cancer cells (through chemotherapy, surgery and radiation) to regarding cancer as a wound that needs to be helped to heal. This thinking was first…

MondayDec 15, 2025 9:45 am

Antisense’s Moment: How Rational Design Is Rewriting Drug Development Economics

Industry data shows small molecules achieve 5–10% approval rates over 15–20 years; antisense oligonucleotides (“ASOs”) are shifting the odds through rational design. Six new antisense drugs gained FDA approval in 2023–2024, bringing total approvals above 20; evidence of accelerating regulatory momentum. Oncotelic Therapeutics’ OT-101 (Trabedersen) is the only TGF-β2-specific antisense in Phase 3 trials, targeting pancreatic cancer and other resistant malignancies. The pharmaceutical industry has long faced sobering odds: about 90% of drug candidates fail before reaching market. For small molecules, approval rates hover at very low odds, often requiring up to two decades of development. In oncology, success rates…

FridayDec 12, 2025 10:00 am

Study Highlights Increasing Cases of Breast Cancer in Younger Women

A study that involved an analysis of patient records in New York has discovered that breast cancer, and especially aggressive forms of this cancer, is occurring at a higher rate among younger women aged below 40. This group is currently regarded as low risk for breast cancer by the existing screening guidelines, and this calls for a review of those guidelines. The study analyzed data spanning 11 years taken from 2014 to the end of 2024. These outpatient records were taken from seven medical facilities that covered an area of approximately 200 miles in Western New York State. The team…

ThursdayDec 11, 2025 10:00 am

Health Experts Suggest How Public Trust Can Be Restored in US Healthcare

After the pandemic, public trust in the U.S. healthcare system plummeted, and officials at the local level took the hardest hit when compared to federal health officials. As things stand, even state and federal health officials are losing even the little trust that the public still had in them. For a healthcare system to function, public trust is vital because people want to believe that the professionals they entrust with their health have their best interests at heart. It is therefore alarming that public trust in healthcare professionals is at an all-time low, and fixing the healthcare crisis needs to…

TuesdayDec 09, 2025 10:00 am

US to End Mandatory Vaccination of Newborns Against Hepatitis B

Since 1991, there has existed a recommendation requiring all newborns to receive a vaccine against Hepatitis B at birth. However, an advisory panel on vaccines voted on Friday to end this recommendation and instead recommended that only babies whose mothers have had a positive test for hepatitis B should receive the shot at birth. The panel in question, ACIP (Advisory Committee on Immunization Practices), advises the CDC on vaccination policy in the U.S. During their recent meeting, the panel voted 8-3 in favor of letting individuals decide whether to have their newborns receive the vaccine or not. This only applies…

MondayDec 08, 2025 9:00 am

Soligenix Inc. (NASDAQ: SNGX) Receives Strong Vote of Confidence from Zacks Report Despite Muted Market Response to Clinical Milestone

The report maintains $25 per share valuation for Soligenix, based on a probability-adjusted discounted cash flow model that considers potential future revenues. The centerpiece of the Zacks analysis focuses on what is characterized as a “very encouraging” 48% blinded response rate. With 50 patients now enrolled out of a planned 80-patient study, the company remains on track for the interim analysis to occur in the second quarter of 2026. When a late-stage clinical trial reports response rates nearly double what researchers expected, yet the stock market barely reacts, seasoned analysts take notice and wonder if investors are missing something significant.…

FridayDec 05, 2025 10:00 am

Nasal Drops Hold Promise in Fighting Deadly Brain Cancer

The fight against glioblastoma, a deadly brain cancer, has been boosted by new research conducted at Washington University that has developed nasal drops which can travel through nerves found in the nose and reach different parts of our central nervous system in order to fight the glioblastoma cells there. Preliminary results revealed that this novel medication safely reached the intended target and protected the mice against the fatal tumors. Alexander Stegh, a neurosurgeon at the university, explains that their approach offers hope for more effective and safer treatments for this deadliest brain cancer and possibly other cancers that are resistant…

ThursdayDec 04, 2025 10:00 am

Cancer Immunotherapy Could Be Boosted by Targeting Pathways of DNA Repair

A newly published study shows that the fight against cancer could be boosted by considering approaches that seek to disrupt the mechanisms through which tumor cells respond to damage to their DNA. Targeting these pathways could make immunotherapy more effective for a lot more people. The study team led by Tang Z. focused on DDR (DNA Damage Response), a process at the cellular level in which cells undertake a variety of measures to fix any damage to their DNA. This repair process is intended to keep the tumor functioning and able to continue growing and spreading. By disrupting DDR, cancer…

ThursdayDec 04, 2025 9:00 am

Breakthrough Therapies Advance as Rare Disease Burden Intensifies Across Aging Populations

BioMedWire Editorial Coverage: Chronic illnesses and rare disorders among older Americans represent a rapidly intensifying challenge for the U.S. healthcare system, with the National Institutes of Health estimating that more than 30 million people nationwide are living with a rare disease. Most of these conditions have no FDA-approved therapies, leaving older adults particularly at risk as age-related changes can mask or delay accurate diagnosis. This growing strain on care has heightened the need for novel treatments that address significant unmet medical needs. Soligenix Inc. (NASDAQ: SNGX) (profile), a late-stage biopharmaceutical developer, is advancing several rare-disease therapies, including HyBryte[TM] (synthetic hypericin)…

TuesdayDec 02, 2025 10:00 am

Could Copying Lessons from Europe Help America Fix its Healthcare System?

The steep cost of healthcare in the U.S. has always been, and is becoming an even bigger political issue with each passing year. The issue was at the center of the recent shutdown of the federal government and the shutdown was only ended after a promise that the expiring healthcare subsidies would be voted on this month. Health insurance costs are soaring while citizens grapple with a high cost of living. According to a report published by the OECD last month, the per capita expenditure on healthcare in the U.S. far exceeds the per capita cost in other countries. Despite…