March 2025 - BioMedWire (BMW)

WednesdayMar 19, 2025 9:00 am

Clene Inc.’s (NASDAQ: CLNN) CNM-Au8(R) Delivers Significant Survival Benefits in New Analyses of Healey ALS Platform Trial Data

Clene's CNM-Au8® treatment was demonstrated to improve survival in ALS patients by up to 14.8 months. The findings come from a post hoc analysis of the HEALEY ALS Platform Trial, comparing CNM-Au8 to a concurrently enrolled control. Strong survival benefit was observed in patients meeting the planned criteria for Clene’s upcoming Phase 3 RESTORE-ALS trial. The company is preparing to submit a New Drug Application (“NDA”) to the FDA later this year for potential accelerated approval, and further regulatory discussions and a confirmatory Phase 3 trial are planned for mid-2025. Clene (NASDAQ: CLNN) and its wholly owned subsidiary, Clene Nanomedicine…

TuesdayMar 18, 2025 10:00 am

The Clock is Ticking if You Wish to Reconsider Your Medicare Advantage Plan

The open enrollment period for Medicare Advantage (MA) is on until the end of March. If you have been thinking about changing your medical plan, time is running out and you need to act fast. However, your decision shouldn’t be a rushed one as many considerations need to be weighed before you make any decisions. For starters, why would anyone think of changing their MA plan at this time? Many people have their preferred doctors or medical specialists and when those professionals are no longer in the preferred network of their plan provider, it is understandable to switch plans and…

FridayMar 14, 2025 10:00 am

The Brain’s ‘Cleanup Crew’ Could Hold the Key to Alzheimer’s Treatment, Study Shows

A new study conducted by a team at Northwestern University suggests that the brain’s immune cells can be enhanced so that they remove amyloid beta plaques more effectively. Amyloid beta plaques are the toxic proteins that form sticky clumps leading to the development of neurodegenerative diseases like Alzheimer’s. This new discovery could trigger a revolution in the thinking behind current AD treatments and future varieties may benefit from the insights obtained from this study. Efforts have been undertaken to develop AD vaccines, but patients have serious immune responses to these drugs which can cause potentially life-threatening inflammation in the brain.…

FridayMar 14, 2025 9:00 am

Adageis to Launch Series A Funding Round, Seeking $10M in Growth Capital

Adageis is opening a Series A funding round, capital raise, aiming to raise $10 million for growth and expansion. The company previously closed a $2 million seed round in Q4 2024 to enhance operations and market reach. Adageis expects to exceed growth targets for Q1 2025, with strong market adoption of its AI-powered platform designed to streamline healthcare operations, optimize revenue, and improve patient care outcomes. The company has cut onboarding time from four weeks to one week, accelerating customer acquisition and revenue growth. Adageis, a healthcare technology company reshaping patient care through flexible AI-centric software solutions for healthcare organizations,…

ThursdayMar 13, 2025 10:00 am

Why it is Crucial to Prepare Healthcare Data for Use in AI Models

The rate at which AI is being integrated in healthcare is accelerating. However, data quality is often lacking, and this reduces the effectiveness of many AI solutions tailored to the healthcare industry. Given that healthcare data is often siloed, the vast majority of this data is unstructured. This can pose challenges in the use of this data for AI models since the insights extracted could be biased or have other defects. Data needs to be consistent in the way it is presented, its quality must be high and the formats need to be standardized. Otherwise, the data could be misinterpreted…

ThursdayMar 13, 2025 9:45 am

Soligenix Inc. (NASDAQ: SNGX) Is ‘One to Watch’

Soligenix has multiple late-stage assets with orphan and fast-track designations, providing a clear regulatory pathway toward potential approvals. The company’s pipeline has a total addressable market exceeding $2 billion, spanning rare diseases, inflammation, and biothreat applications. Soligenix has benefited from significant non-dilutive government funding, which reduces operational expenses and financial risk while supporting its public health initiatives. The company is well-positioned for multiple development and regulatory catalysts, and commercial milestones, with lead candidates in cutaneous T-cell lymphoma, psoriasis, oral mucositis, and Behçet’s disease. Soligenix is led by an experienced management team with a strong track record of success. Soligenix (NASDAQ:…

WednesdayMar 12, 2025 9:00 am

Clene Inc. (NASDAQ: CLNN) to Present CNM-Au8(R) Updates at 37th Annual Roth Conference

The 37th Annual Roth Conference, to be held March 16-18 in Dana Point, California, will showcase the broadest group of companies in the event’s history, with senior executives from approximately 500 companies across various industries, including business services, consumer, healthcare, insurance, sustainability and technology, media and entertainment. Clene’s management will participate in a virtual fireside chat at 9:20 a.m. PST on March 18, as well as one-on-one investor meetings during the event. During the fireside chat and in investor meetings, the company will detail recent achievements and next steps for lead drug candidate CNM-Au8 for ALS and MS. Clene Inc.…

TuesdayMar 11, 2025 10:00 am

Study Finds Experimental Drug Prolongs the Survival of Glioblastoma Patients

A recent study whose findings appeared in the Nature Communications journal has shown that a new experimental drug can increase the survival time of patients who have been diagnosed with glioblastoma. This brain cancer is the most prevalent brain cancer in adults. The experimental drug, dubbed 186RNL (Rhenium Obisbemeda), was developed at UT Health San Diego. The trial established that this drug candidate, at the very least, doubled the progression-free and survival duration of study participants in comparison to the known progression-free or survival rates of patients afflicted by this brain tumor. It also didn’t have any side effects that…

FridayMar 07, 2025 10:00 am

Bacterial Imbalances Have a Link to Multiple Sclerosis, Study Finds

Approximately a million Americans suffer from multiple sclerosis (MS), and globally, more than 2.8 million individuals have this condition. Several factors are thought to play a role in the development of this autoimmune condition, such as genetics, environmental factors, infectious disease, diet, and gut health. A new study has shown that imbalances in certain types of gut bacteria not only strongly indicate the likelihood of this illness developing but could also be a pointer to the severity of the disease in affected individuals. The researchers discovered that the ratio of two specific bacteria in the gut was a strong predictor…

FridayMar 07, 2025 10:00 am

Adageis Secures $2M Seed Funding to Expand AI-Driven Healthcare Solutions

Adageis closed a $2 million seed round at the end of Q4 2024 to support operational expansion, with the funding to enhance backend operations for next-generation software upgrades. Upgraded Electronic Health Record EHR”) connectivity will facilitate integration with over 90 EHR systems, while increased sales force investment will help accelerate growth and market adoption. Adageis’ AI-powered platform is designed to streamline healthcare operations, optimize provider revenue, and improve patient care outcomes. Adageis, a forward-thinking healthcare technology company reshaping patient care through flexible AI-centric software solutions for healthcare organizations, has secured $2 million in seed financing to enhance its operations and…