New Drug Approach Could Roll Back Pancreatic Cancer Immunotherapy Resistance
New research by scientists from the Oregon Health & Science University and Johns Hopkins Kimmel Cancer Center has found a new approach that can make tumors resistant to immunotherapy vulnerable to the treatment. For their study, the researchers evaluated the effectiveness and safety of the combination of 2 medications; entinostat, an epigenetic drug; and nivolumab, an immunotherapy medication. The drugs were administered to a group of twenty-seven patients with advanced pancreatic ductal adenocarcinoma. The patients had in the past undergone chemotherapy. The immune activity in the microenvironment of patients with this common type of pancreatic cancer is suppressed, which allows…











