WednesdayDec 06, 2023 10:30 am

PaxMedica Inc. (NASDAQ: PXMD) Completes Key Type-B FDA Meeting, Discussing Positive Results from PAX-HAT-301 Study

During the live type-B meeting, PaxMedica discussed the positive results of the recent data from its PAX-HAT-301 study of suramin in Stage One HAT, also called African Sleeping Sickness The FDA is allowing PaxMedica to use previous data from early tests of suramin to begin developing the drug for use in current cases of HAT PaxMedica received constructive feedback, which will aid in completing the remaining work necessary to file a New Drug Application (“NDA”), expected in the second half of 2024 The global ASD therapeutics market was valued at $1.93 billion in 2022 and is expected to reach $3.42…

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TuesdayDec 05, 2023 3:31 pm

Already-Approved Treatments Could Be Tested in Fight Against Brain Metastasis

A recent review of research papers on brain cancers that have metastasized to the lungs has discovered that already-approved treatments could be clinically tested as potential therapies against brain metastasis. The University of Bristol study also discovered genetic differences between smokers and nonsmokers. Brain cancer metastasis affects roughly 25,000 patients in the United Kingdom, with the cancers typically originating from the lungs or breasts and causing death in most of this patient class. Although substantial research efforts have been dedicated toward understanding primary lung cancer genetic mutation, much less is known about the cancer’s genetic environment once it spreads to…

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TuesdayDec 05, 2023 9:00 am

PaxMedica Inc. (NASDAQ: PXMD) Closes Public Offering of Approximately $7 Million and Continues Pursuing ASD Pipeline

PaxMedica’s total gross proceeds from the offering, before deducting the placement agent’s fees and other offering expenses, were approximately $7 million The company intends to use the proceeds to pay an outstanding promissory note, advance development programs, and general corporate purposes PaxMedica received constructive feedback from its type-B meeting with the FDA, which will aid in completing the remaining paperwork necessary to file a New Drug Application The company is currently working on commercial lots of PAX-101, which are expected during the first half of 2024, for the New Drug Application, which is expected to be filed during the second…

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MondayDec 04, 2023 12:32 pm

Topical Analgesics Emerge as Important Pain-Management Tools

Estimates from the Centers for Disease Control and Prevention (CDC) show that more than 50 million individuals in America experienced chronic pain in 2021. Chronic pain is a common reason for patients to seek medical care. It can significantly impact an individual’s daily life as well as overall quality of life in the long-term, which makes its treatment crucial. Currently, opioids are commonly prescribed to help manage chronic pain. It is estimated that roughly 20% of patients who suffer from persistent pain are prescribed opioids. With the current opioid crisis affecting states across America and the fact that prescribed opioids…

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FridayDec 01, 2023 11:55 am

Study Shows Autistic People Have Lower Life Expectancy Than General Population

Autism spectrum disorder is a developmental and neurological disorder that affects how an individual interacts with others, as well as learns, behaves and communicates. While some individuals on the spectrum can learn to be independent, others require long-term support and care.  Additionally, individuals on the autism spectrum are more likely to have mental-health conditions, with data showing that suicide rates are higher in this particular group. New research has found that individuals with autism who also have learning disabilities have heightened chances of dying prematurely in comparison to the general public. The researchers’ objective was to look into whether autism…

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ThursdayNov 30, 2023 12:19 pm

Hidden Belly Fat Could Be a Precursor of Alzheimer’s Onset Years Later

Alzheimer’s is a progressive illness that often begins with mild loss of memory and confusion. This type of dementia involves parts of the brain that control memory, thought and language. Patients in very severe decline often have difficulty carrying out daily activities, which may include holding a conversation or responding to the environment. As of 2020, estimates showed that about 5.8 million individuals in America were living with Alzheimer’s disease. Projections show that one in every five women and one in every ten men will develop this condition in their lifetime. While the exact cause of the disease isn’t known,…

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WednesdayNov 29, 2023 2:31 pm

Study Suggests Parkinson’s Could Be Linked to Onset of Stroke, Heart Disease

A study recently published in the “Scientific Reports” journal has found a potential link between Parkinson’s, strokes and the onset of heart disease. Researchers behind the study used a two-sample Mendelian randomization analysis to find links associations between cardiocerebrovascular illnesses and Parkinson’s disease (PD). While some past studies have surmised that cardiocerebrovascular conditions and PD are related, those studies are relatively controversial. The research team sought to investigate the potential effect of PD on cardiocerebrovascular disorders via the Mendelian randomization method. It leveraged data from 482,730 Europeans in the International PD Genomics Consortium’s publicly available genome-wide association study (GWAS) in…

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TuesdayNov 28, 2023 12:31 pm

Autoimmunity Patients Face Cost, Diagnosis, Care Challenges

Autoimmune diseases occur when the immune system becomes dysfunctional and begins attacking healthy tissue and organs. More than 20 million Americans suffer from a myriad of autoimmune diseases, such as thyroid disease, rheumatoid arthritis and lupus, that can significantly impact their quality of life. Many autoimmune patients often have to deal with years of misdiagnosis and untreated symptoms before they finally receive a proper diagnosis. Since a majority of autoimmune diseases have no cure, patients such as Beth VanOrden from Athens, Texas, have to take various medications to manage symptoms for the rest of their lives. VanOrden suffers from Hashimoto’s…

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MondayNov 27, 2023 2:22 pm

Study Says Patients on Gene Therapy Need Long-Term Monitoring

Sickle cell disease is a genetic illness that modifies the shape of red blood cells into a crescent or sickle shape, causing serious health issues and heightening the risk of patients developing blood cancer. A recently conducted study has found promising results concerning gene therapy’s potential in curing genetic illnesses. These findings providing new insights into what happens in the human body following treatment. For their study, the researchers examined samples obtained from sickle cell disease patients who underwent gene therapy as part of a trial conducted by Boston Children’s Hospital. They then observed the genetic changes in each patient’s…

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MondayNov 27, 2023 10:30 am

SOHM Inc. (SHMN) Is ‘One to Watch’

In August 2023, SOHM signed an LOI with CGA Intellectual Holdings Inc. to acquire disruptive stem cell technology and patents The company announced in July 2023 it had closed on the needed financing for its various ongoing projects SOHM announced in April 2023 it had signed an exclusive distribution agreement for its latest product, the anticonvulsant Levetiracetam The company in March 2023 introduced its new topical skincare line of products SOHM (OTC: SHMN) is a generic pharmaceutical manufacturing and marketing company with a vision of “Globalè Prospèro” (Global Prosperity). SOHM was founded in 1998 and is headquartered in Chino Hills,…

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