Light, Viruses Could Transform Brain-Tumor Treatment

A biomedical researcher from Spain has spent the past several years working on a novel brain-tumor treatment that would expand the boundaries of medical innovation to unseen territories. Dr. Marta Alonso shifted her focus to pediatric brain tumors after she met a teenager with medulloblastoma at the MD Anderson Cancer Center in Houston more than 15 years ago.

Medulloblastoma is a common pediatric cancerous brain tumor that typically starts growing in the cerebellum, the lower back region of the brain that is involved in movement, balance and muscle coordination. Treatment protocols for the pediatric cancer involve surgery, radiation, and chemotherapy, and the condition has a five-year survival rate of 72% for children aged 14 and younger.

Although many medulloblastoma patients have benefitted significantly from current treatments, researchers such as Alonso are working on innovative treatments that would ensure no medulloblastoma patient is left behind. Alonso developed a novel treatment that involves using modified viruses to stimulate the natural immune response and trigger certain genetic pathways to make immune cells attack cancer cells more aggressively. This treatment is somewhat similar to immunotherapy as it focuses on empowering the human immune system to fight tumorous cancer cells rather than killing them itself.

With financial backing from the European Union, Alonso launched the research project ViroPedTher, which focuses on developing treatments for atypical teratoid rhabdoid tumors and gliomas, two rare tumors that tend to develop deep within children’s brains. The project aims to begin larger-scale clinical trials by mid-2024 and expand efforts to develop safe and much more effective treatments for pediatric brain tumors.

Lumiblast, another project with EU funding, is looking to leverage light-sensitive compounds such as protoporphyrin IX in the development of noninvasive brain cancer treatment. Surgery is an effective means of cutting out brain tumors, but it is incredibly invasive and wrought with many potential risks. These risks includes infection, blood clots, swelling and bleeding in the brain, seizures, allergic reactions to anesthesia and impaired motor skills or memory.

Dr. Theodossis Theodossiou and his team at the Lumiblast project are working on a light-based treatment that could destroy cancer cells in the brain without the need for surgery. The research team is currently looking for compounds that can help locate tumors in the brain by causing a chemical reaction that makes them “glow,’ allowing for precise and accurate brain tumor locating.

While the project will have to overcome issues such as low-light penetration into brain tissues, it is opening the door to the development of completely novel pathways for treating brain tumors.

With other enterprises such as CNS Pharmaceuticals Ltd. (NASDAQ: CNSP) also engaged in searching for effective treatments against pediatric and adult-onset brain cancers, a breakthrough for patients could happen sooner rather than later.

NOTE TO INVESTORS: The latest news and updates relating to CNS Pharmaceuticals Inc. (NASDAQ: CNSP) are available in the company’s newsroom at

About BioMedWire

BioMedWire (“BMW”) is a specialized communications platform with a focus on the latest developments in the Biotechnology (BioTech), Biomedical Sciences (BioMed) and Life Sciences sectors. It is one of 60+ brands within the Dynamic Brand Portfolio @ IBN that delivers: (1) access to a vast network of wire solutions via InvestorWire to efficiently and effectively reach a myriad of target markets, demographics and diverse industries; (2) article and editorial syndication to 5,000+ outlets; (3) enhanced press release enhancement to ensure maximum impact; (4) social media distribution via IBN to millions of social media followers; and (5) a full array of tailored corporate communications solutions. With broad reach and a seasoned team of contributing journalists and writers, BMW is uniquely positioned to best serve private and public companies that want to reach a wide audience of investors, influencers, consumers, journalists and the general public. By cutting through the overload of information in today’s market, BMW brings its clients unparalleled recognition and brand awareness.

BMW is where breaking news, insightful content and actionable information converge.

To receive SMS alerts from BioMedWire, “Biotech” to 888-902-4192 (U.S. Mobile Phones Only)

For more information, please visit

Please see full terms of use and disclaimers on the BioMedWire website applicable to all content provided by BMW, wherever published or re-published:

San Francisco, CA
415.949.5050 Office

BioMedWire is powered by IBN


Select A Month

Official NewsWire Relationships

BIO Informa DGE Dynamic Global Events DTC Healthcare Conference Kiasco Reasearch Nexus Conferences Octane

BioMedWire Currently Accepts



Bitcoin Cash

Bitcoin Cash





USD Coin

USD Coin

Contact us: 415.949.5050