Recently, Professor Federica Sotgia and Professor Michael Lisanti made a discovery that could make cancer a treatable ailment.
For many years, billions of dollars have been poured into the field of cancer research in an effort to find ways to treat and cure the disease. However, there are still no FDA/MHRA approved drugs that combat metastasis. As a result, cancer metastasis, which is lethal, remains an untreatable and mysterious disease.
For those who may not be completely familiar with cancer metastasis; this is when cancer cells spread throughout the body’s organs such as the lungs, bone tissue, the brain and the liver. Metastasis turns the cancer into a terminal illness that it untreatable as there are no effective therapies that are available.
When the cancer is present in other organs and tumors have grown in those organs, doctors may advise for tumor removal, depending on your cancer’s progress and treatment procedure. Usually, after the primary tumor has been surgically removed, many cancer patients undergo radiation and chemotherapy to eliminate the remaining tumor cells that may have remained in the body. Unfortunately, most cancer patients experience tumor recurrence, which results in the cancer spreading.
Consequently, more than 90% of these cancer patients who experience treatment failure lose their lives to metastatic disease. Now researchers at the University of Salford have discovered that ATP-depletion is the weakness of metastasis. This depletion can be accomplished by removing the cancer cell’s capacity to make new energy.
Therefore, the discovery by Professor Federica Sotgia and Professor Michael Lisanti of metastasis inhibitors that could turn cancer into a chronic disease that is treatable is a remarkable feat. Both professors, who work at the University of Salford in Translational Medicine, have created and evaluated new cancer metastasis inhibitors which are based on Doxycycline, which is an FDA-approved antibiotic that was first approved in 1967.
They chemically modified Doxycycline, making it 5 times more powerful in attacking metastatic cancer cells. This modification to the Doxycycline antibiotic also renders it ineffective when used as an antibiotic, which effectively eliminates the risk of developing antibiotic resistant infections and bacteria.
Additionally, Doxy-Myr, the new modified drug, has an added fatty acid that is non-toxic, as seen in pre-clinical studies. While clinical trials are being conducted to determine the efficacy of this drug in helping prevent metastasis as well as help design drugs that will prevent metastasis, this breakthrough could change how cancer is treated. The addition of metastasis prevention as an effective way to treat cancer shows incredible progress in cancer research.
Analysts believe that is discovery is likely to be of great interest to lots of biomedical companies like 180 Life Sciences Corp.
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