Why Depression Often Makes You Feel Tired

People who suffer from depression usually report that they feel so fatigued that even mundane tasks, such as leaving their beds, are very difficult to manage. According to research, approximately 90% of all the people with major depressive disorder suffer from fatigue. Here are some of the reasons why you may feel fatigued if you suffer from depression.

Sleep Problems

Sleep is essential because it allows the body to replenish its energy supplies and to recover from any damage sustained during the waking hours. If you are depressed, you are likely to have difficulties falling asleep or even staying asleep. This sleep deprivation means that your energy reserves aren’t being replenished as they should, and that accounts for the tiredness you feel.

Other sleep problems, such as obstructive sleep apnea and hypersomnia (constantly feeling sleepy), also increase fatigue.

Your Diet

A meta study done in 2018 found some evidence that a diet which is rich in inflammation-causing foods, such as processed meats, increased one’s likelihood for developing depression and the fatigue associated with those poor dietary choices.

Furthermore, people who are depressed often lack the motivation to be mindful when choosing what to eat, and this increases the odds that they will select foods which aren’t healthy. Such foods will increase the fatigue that the person feels.


Stress wreaks havoc one’s dopamine and serotonin levels and yet these neurotransmitters play a major role in determining your energy levels and mood. Since chronic stress is usually behind the onset of depression, it is therefore not surprising that when you are depressed, you will feel fatigued all the time.

Research also shows that stress can trigger inflammation in different parts of the body, and that inflammation will sap your energy and leave you feeling fatigued.

Some Medications

Antidepressants help the neurotransmitters in the brain to be more effective at regulating your mood, and therefore alleviate depression. However, some antidepressants have the side effect of making a patient to feel fatigued, and that may explain why you may be feeling tired all the time yet you are taking your medication to combat depression.

There are different coping mechanisms which can help if you are constantly depressed and tired, but perhaps the most important one, which biomedical companies like CNS Pharmaceuticals Inc. (NASDAQ: CNSP) would be likely to recommend, is for you to talk to an experienced doctor. This professional will assess you before designing an intervention protocol to help you get better. For example, they may prescribe different medication if what you are currently taking is causing you to feel tired all the time.

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